Combination Interventions to Prevent HCV Transmission Among People Who Inject Drugs: Modeling the Impact of Antiviral Treatment, Needle and Syringe Programs, and Opiate Substitution Therapy
Author(s) -
Natasha K. Martin,
Matthew Hickman,
Sharon Hutchinson,
David Goldberg,
Peter Vickerman
Publication year - 2013
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cit296
Subject(s) - medicine , syringe , hepatitis c , psychological intervention , incidence (geometry) , opiate substitution treatment , transmission (telecommunications) , hepatitis c virus , antiviral therapy , chronic hepatitis , immunology , virus , buprenorphine , physics , receptor , electrical engineering , psychiatry , opioid , optics , engineering
Interventions such as opiate substitution therapy (OST) and high-coverage needle and syringe programs (HCNSP) cannot substantially reduce hepatitis C virus (HCV) prevalence among people who inject drugs (PWID). HCV antiviral treatment may prevent onward transmission. We project the impact of combining OST, HCNSP, and antiviral treatment on HCV prevalence/incidence among PWID.
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