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Performance of United States Serologic Assays in the Diagnosis of Lyme Borreliosis Acquired in Europe
Author(s) -
John A. Branda,
Franc Strle,
Klemen Strle,
Nikhil Sikand,
Mary Jane Ferraro,
Allen C. Steere
Publication year - 2013
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cit235
Subject(s) - medicine , serology , lyme disease , lyme borreliosis , european union , immunology , european standard , gold standard (test) , virology , borrelia burgdorferi , antibody , architectural engineering , business , engineering , economic policy
Physicians in the United States sometimes need to evaluate a patient for suspected Lyme borreliosis (LB) who may have acquired the infection in Europe. Using serum samples from European LB patients, we compared the performance of European and US serodiagnostic tests, including newer-generation assays containing Vmp-like sequence, expressed or its C6 peptide.

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