An Intensive Longitudinal Cohort Study of Malian Children and Adults Reveals No Evidence of Acquired Immunity to Plasmodium falciparum Infection | Zendy

Tuan M. Tran | Zendy; Shanping Li | Zendy; Safiatou Doumbo | Zendy; Didier Doumtabé | Zendy; Chiung Yu Huang | Zendy; Seydou Dia | Zendy; Aboudramane Bathily | Zendy; Jules Sangala | Zendy; Younoussou Koné | Zendy; Abdrahamane Traoré | Zendy; Moussa Niangaly | Zendy; Charles Dara | Zendy; Kassoum Kayentao | Zendy; Aissata Ongoïba | Zendy; Ogobara K. Doumbo | Zendy; Boubacar Traoré | Zendy; Peter D. Crompton | Zendy

Open Access

An Intensive Longitudinal Cohort Study of Malian Children and Adults Reveals No Evidence of Acquired Immunity to Plasmodium falciparum Infection

Author(s) -

Tuan M. Tran,

Shanping Li,

Safiatou Doumbo,

Didier Doumtabé,

Chiung Yu Huang,

Seydou Dia,

Aboudramane Bathily,

Jules Sangala,

Younoussou Koné,

Abdrahamane Traoré,

Moussa Niangaly,

Charles Dara,

Kassoum Kayentao,

Aissata Ongoïba,

Ogobara K. Doumbo,

Boubacar Traoré,

Peter D. Crompton

Publication year - 2013

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cit174

Subject(s) - malaria , plasmodium falciparum , immunity , medicine , immunology , asymptomatic , population , parasitemia , biology , immune system , environmental health

In experimental models of human and mouse malaria, sterilizing liver stage immunity that blocks progression of Plasmodium infection to the symptomatic blood stage can be readily demonstrated. However, it remains unclear whether individuals in malaria-endemic areas acquire such immunity.

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