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The Immunomodulatory Nutritional Intervention NR100157 Reduced CD4+ T-Cell Decline and Immune Activation: A 1-Year Multicenter Randomized Controlled Double-Blind Trial in HIV-Infected Persons Not Receiving Antiretroviral Therapy (The BITE Study)
Author(s) -
Pedro Cahn,
Kiat Ruxrungtham,
Brian Gazzard,
Ricardo Sobhie Diaz,
Andrea Gori,
Donald P. Kotler,
Aldwin J. M. Vriesema,
Niki Georgiou,
Johan Garssen,
Mario Clerici,
Joep M. A. Lange
Publication year - 2013
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cit171
Subject(s) - medicine , immunology , randomized controlled trial , immune system , human immunodeficiency virus (hiv) , immunopathology , antiretroviral therapy , sida , viral disease , multicenter trial , clinical trial , viral load , multicenter study
The immunomodulatory nutritional product NR100157 was developed for human immunodeficiency virus (HIV)-infected individuals. We hypothesized that targeting the compromised gastrointestinal tract of HIV-infected individuals would result in systemic immunological benefits.

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