Prophylactic Effect of Antiretroviral Therapy on Hepatitis B Virus Infection
Author(s) -
Hiroyuki Gatanaga,
Tsunefusa Hayashida,
Junko Tanuma,
Shinichi Oka
Publication year - 2013
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cit145
Subject(s) - medicine , lamivudine , hepatitis b virus , virology , hepatitis b , antiretroviral therapy , virus , human immunodeficiency virus (hiv) , immunology , viral load
Hepatitis B virus (HBV) infection is common in individuals infected with human immunodeficiency virus, especially in men who have sex with men (MSM). Almost all currently used regimens of antiretroviral therapy (ART) contain lamivudine (LAM) or tenofovir disoproxil fumarate (TDF), both of which have significant anti-HBV activity. However, the prophylactic effect of ART on HBV infection has not been assessed previously.
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