Specific Interferon γ Detection for the Diagnosis of Previous Q Fever | Zendy

Teske Schoffelen | Zendy; Leo A. B. Joosten | Zendy; Tineke Herremans | Zendy; Anton F. J. de Haan | Zendy; Anne Ammerdorffer | Zendy; H. C. Rümke | Zendy; Clementine Wijkmans | Zendy; H.I.J. Roest | Zendy; Mihai G. Netea | Zendy; J.W.M. van der Meer | Zendy; Tom Sprong | Zendy; Marcel van Deuren | Zendy

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Specific Interferon γ Detection for the Diagnosis of Previous Q Fever

Author(s) -

Teske Schoffelen,

Leo A. B. Joosten,

Tineke Herremans,

Anton F. J. de Haan,

Anne Ammerdorffer,

H. C. Rümke,

Clementine Wijkmans,

H.I.J. Roest,

Mihai G. Netea,

J.W.M. van der Meer,

Tom Sprong,

Marcel van Deuren

Publication year - 2013

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cit129

Subject(s) - coxiella burnetii , serology , q fever , medicine , concordance , immunology , antigen , virology , antibody

Current practice for diagnosis of Q fever, caused by the intracellular pathogen Coxiella burnetii, relies mainly on serology and, in prevaccination assessment, on skin tests (STs), which both have drawbacks. In this study, C. burnetii-specific interferon γ (IFN-γ) production was used as a new diagnostic tool for previous Q fever, circumventing most of these drawbacks. Our aim was to compare this test to serology and ST.

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