Open AccessThe Safety of Amphotericin B Lipid Complex in Patients With Prior Severe Intolerance to Liposomal Amphotericin B
Author(s) -
Dimitrios Farmakiotis,
Frank Tverdek,
D. P. Kontoyiannis
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis972
Subject(s) - amphotericin b , tolerability , medicine , confidence interval , adverse effect , pharmacology , gastroenterology , antifungal , dermatology
The tolerability of amphotericin B lipid complex in patients with previous severe infusion reactions to liposomal amphotericin B is unclear. We reviewed the charts of 40 such patients at a tertiary care cancer center and found that amphotericin B lipid complex administration was uneventful in 34 patients (85% [95% confidence interval, 69%-93%]).
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