Extended-Spectrum β-Lactamase–Producing Escherichia coli From Retail Chicken Meat and Humans: Comparison of Strains, Plasmids, Resistance Genes, and Virulence Factors
Author(s) -
Jan Kluytmans,
I. T. M. A. Overdevest,
Ina Willemsen,
Marjolein Kluytmans-van den Bergh,
Kim van der Zwaluw,
Max Heck,
Martine C. Rijnsburger,
Christina M. J. E. VandenbrouckeGrauls,
Paul H. M. Savelkoul,
Brian Johnston,
David M. Gordon,
James R. Johnson
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis929
Subject(s) - virulence , pulsed field gel electrophoresis , biology , plasmid , multilocus sequence typing , escherichia coli , microbiology and biotechnology , amplified fragment length polymorphism , gene , replicon , genetics , mobile genetic elements , genotype , genetic diversity , population , medicine , environmental health
The worldwide prevalence of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae is increasing rapidly both in hospitals and in the community. A connection between ESBL-producing bacteria in food animals, retail meat, and humans has been suggested. We previously reported on the genetic composition of a collection of ESBL-producing Escherichia coli (ESBL-EC) from chicken meat and humans from a restricted geographic area. Now, we have extended the analysis with plasmid replicons, virulence factors, and highly discriminatory genomic profiling methods.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom