Antiretroviral Drug-Related Liver Mortality Among HIV-Positive Persons in the Absence of Hepatitis B or C Virus Coinfection: The Data Collection on Adverse Events of Anti-HIV Drugs Study
Author(s) -
Helen Kovari,
Caroline Sabin,
Bruno Ledergerber,
Lene Ryom,
Signe Westring Worm,
Colette Smith,
Andrew Phillips,
Peter Reiss,
Éric Fontas,
Kathy Petoumenos,
Stéphane De Wit,
Philippe Morlat,
Jens Lundgren,
Rainer Weber
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis919
Subject(s) - medicine , coinfection , hepatitis c , hepatitis c virus , hepatitis b , adverse effect , mortality rate , hepatitis b virus , incidence (geometry) , immunology , virology , human immunodeficiency virus (hiv) , virus , physics , optics
Liver diseases are the leading causes of death in human immunodeficiency virus (HIV)-positive persons since the widespread use of combination antiretroviral treatment (cART). Most of these deaths are due to hepatitis C (HCV) or B (HBV) virus coinfections. Little is known about other causes. Prolonged exposure to some antiretroviral drugs might increase hepatic mortality.
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