Risk Factors and Primary Prevention of Congenital Chagas Disease in a Nonendemic Country
Author(s) -
Laura Murcia,
Bartolomé Carrilero,
María José Muñoz-Dávila,
M. Carmen Thomas,
Manuel Carlos López,
Manuel Segovia
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis910
Subject(s) - medicine , chagas disease , trypanosoma cruzi , transmission (telecommunications) , cohort , polymerase chain reaction , predictive value , cohort study , disease , longitudinal study , pediatrics , immunology , pathology , parasite hosting , world wide web , computer science , electrical engineering , engineering , biochemistry , chemistry , gene
In this longitudinal cohort study we evaluated the congenital transmission of Chagas disease (CD) in a nonendemic area. The aim of this work was to analyze the predictive value of a Trypanosoma cruzi-positive polymerase chain reaction (PCR) result in pregnant women for the diagnosis of vertical transmission and to evaluate the use of PCR as a tool for early detection of infection.
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