The Clinical and Economic Impact of Genotype Testing at First-line Antiretroviral Therapy Failure for HIV-Infected Patients in South Africa
Author(s) -
Julie H. Levison,
Robin Wood,
Catherine Scott,
Andrea Ciaranello,
Neil Martinson,
Corina Rusu,
Elena Losina,
Kenneth A. Freedberg,
Rochelle P. Walensky
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis887
Subject(s) - life expectancy , genotype , medicine , viral load , cohort , cost effectiveness , demography , human immunodeficiency virus (hiv) , virology , environmental health , biology , population , genetics , risk analysis (engineering) , sociology , gene
In resource-limited settings, genotype testing at virologic failure on first-line antiretroviral therapy (ART) may identify patients with wild-type (WT) virus. After adherence counseling, these patients may safely and effectively continue first-line ART, thereby delaying more expensive second-line ART.
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