Cross-Protective Capacity of Japanese Encephalitis (JE) Vaccines Against Circulating Heterologous JE Virus Genotypes | Zendy

Elina Erra | Zendy; Helena Hervius Askling | Zendy; Sutee Yoksan | Zendy; Lars Rombo | Zendy; Jukka Riutta | Zendy; Sirkka Vene | Zendy; Lars Lindquist | Zendy; Olli Vapalahti | Zendy; Anu Kantele | Zendy

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Cross-Protective Capacity of Japanese Encephalitis (JE) Vaccines Against Circulating Heterologous JE Virus Genotypes

Author(s) -

Elina Erra,

Helena Hervius Askling,

Sutee Yoksan,

Lars Rombo,

Jukka Riutta,

Sirkka Vene,

Lars Lindquist,

Olli Vapalahti,

Anu Kantele

Publication year - 2012

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cis883

Subject(s) - heterologous , virology , genotype , japanese encephalitis , virus , encephalitis , antibody , biology , medicine , immunology , gene , genetics

Current Japanese encephalitis vaccines are derived from strains of genotype III, yet heterologous genotypes are emerging in endemic areas. Inactivated vaccines given to European travelers were found to elicit protective levels of neutralizing antibodies against heterologous strains of genotypes I-IV.

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