Persistence and Antiviral Resistance of Varicella Zoster Virus in Hematological Patients
Author(s) -
Martha T. van der Beek,
Clementien L. Vermont,
Robbert G. M. Bredius,
Erik W.A. Marijt,
Caroline S. de Brouwer,
Aloys C.M. Kroes,
Eric C. J. Claas,
Ann C.T.M. Vossen
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis879
Subject(s) - medicine , varicella zoster virus , virus , persistence (discontinuity) , immunology , hematopoietic stem cell transplantation , disease , viral disease , pediatrics , virology , geotechnical engineering , engineering
Varicella zoster virus (VZV) infections are a relevant cause of morbidity and mortality in hematological patients and especially in hematopoietic stem cell transplant (HSCT) recipients. The present study aimed to investigate the prevalence and clinical significance of viral persistence and antiviral resistance by systematically analyzing all episodes of VZV diagnosed in our laboratory in pediatric and adult hematological patients between 2007 and 2010.
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