Human Adenovirus Infection in Kawasaki Disease: A Confounding Bystander? | Zendy

Preeti Jaggi | Zendy; Adriana E. Kajon | Zendy; Asunción Mejías | Zendy; Octavio Ramilo | Zendy; Amy L. Leber | Zendy

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Human Adenovirus Infection in Kawasaki Disease: A Confounding Bystander?

Author(s) -

Preeti Jaggi,

Adriana E. Kajon,

Asunción Mejías,

Octavio Ramilo,

Amy L. Leber

Publication year - 2012

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cis807

Subject(s) - medicine , kawasaki disease , virology , polymerase chain reaction , virus , typing , viral shedding , viral disease , viral load , immunology , biology , gene , microbiology and biotechnology , biochemistry , artery

Human adenovirus (HAdV) infection mimics Kawasaki disease (KD) but can also be detected in KD patients. Evidence suggests that HAdV-C species can persist in pediatric adenoids and/or tonsils. We sought to determine (1) the frequency of HAdV detection by real-time polymerase chain reaction in KD patients, (2) the differences in HAdV semiquantitative nasopharyngeal viral loads between KD patients with detectable HAdV vs those with HAdV disease, and (3) whether nasopharyngeal HAdV-C shedding is occurring in KD.

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