Acute Otitis Media Replacement and Recurrence in the Finnish Otitis Media Vaccine Trial | Zendy

Janne J. Jokinen | Zendy; Arto A. Palmu | Zendy; Terhi Kilpi | Zendy

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Acute Otitis Media Replacement and Recurrence in the Finnish Otitis Media Vaccine Trial

Author(s) -

Janne J. Jokinen,

Arto A. Palmu,

Terhi Kilpi

Publication year - 2012

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cis799

Subject(s) - medicine , acute otitis media , otitis , pneumococcal conjugate vaccine , clinical trial , pediatrics , disease , surgery , streptococcus pneumoniae , antibiotics , microbiology and biotechnology , biology

We reanalyzed the 7-valent pneumococcal conjugate vaccine trial FinOM for prevention of acute otitis media (AOM), with a focus on disease replacement due to other pathogens and AOM recurrence. We found evidence of replacement disease occurring early during the trial follow-up and little vaccine impact on recurrent overall AOM episodes.

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