Open AccessAdenoviremia Has Limited Clinical Impact in the Majority of Patients Following Alemtuzumab-Based Allogeneic Stem Cell Transplantation in Adults
Author(s) -
Jonathan Sive,
Kirsty Thomson,
Emma Morris,
Katherine N. Ward,
Karl S. Peggs
Publication year - 2012
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis689
Subject(s) - medicine , alemtuzumab , transplantation , stem cell , immunology , oncology , genetics , biology
Adenovirus infection is a potentially serious complication of allogeneic hematopoietic stem cell transplantation (HSCT) and has been reported to occur more frequently following T-cell-depleted reduced-intensity HSCT. However, the true incidence and clinical significance as well as the relationship of disease to viremic titer remain unclear due to wide variation in study populations and methodology.