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Fluoroquinolones and the Risk of Serious Arrhythmia: A Population-Based Study
Author(s) -
Francesco Lapi,
Machelle Wilchesky,
Abbas Kezouh,
Jacques I. Benisty,
Pierre Ernst,
Samy Suissa
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis664
Subject(s) - medicine , gatifloxacin , moxifloxacin , relative risk , rate ratio , confidence interval , cohort , population , cohort study , incidence (geometry) , cardiac arrhythmia , atrial fibrillation , ciprofloxacin , antibiotics , environmental health , microbiology and biotechnology , biology , physics , optics
Fluoroquinolones have been suspected to cause cardiac arrhythmia but data are lacking, particularly for the individual fluoroquinolones. We assessed the risk of serious arrhythmia, defined as ventricular arrhythmia or sudden/unattended death identified in hospital discharge diagnoses, related to fluoroquinolones as a class as well as for each individual molecule.

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