Clostridium difficile Carriage in Healthy Infants in the Community: A Potential Reservoir for Pathogenic Strains
Author(s) -
Clotilde Rousseau,
I. Poîlane,
Loïc de Pontual,
A.-C. Maherault,
Alban Le Monnier,
Anne Collig
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis637
Subject(s) - colonization , clostridium difficile , carriage , medicine , asymptomatic carrier , asymptomatic , ribotyping , microbiology and biotechnology , genotype , pathogen , pediatrics , biology , immunology , antibiotics , gene , pathology , biochemistry
Clostridium difficile has long been considered to be a nosocomial pathogen but has emerged in the community in recent years. During infancy, asymptomatic C. difficile colonization is common. However, knowledge of colonization determinants and strain characteristics is limited. We studied the dynamics of C. difficile colonization in healthy infants from the community. Determinants of colonization and strain genotypes were also determined in a cohort of infants attending day nurseries.
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