Complicated Atazanavir-Associated Cholelithiasis: A Report of 14 Cases
Author(s) -
S. Rakotondravelo,
Y. Poinsig,
F. Borsa-Lebas,
A. de La Blanchardière,
Christophe Michau,
Hélène Jantzem,
N. Massy,
E. Polard,
F. Giroux,
Hélène Kerspern,
A. Meskar,
G. Hue,
Olivier Tribut,
C. Arvieux,
Pierre Tattevin
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis620
Subject(s) - atazanavir , medicine , human immunodeficiency virus (hiv) , regimen , antiretroviral therapy , virology , viral load
Fourteen human immunodeficiency virus (HIV)-infected patients receiving an atazanavir (ATV)-based antiretroviral regimen developed complicated cholelithiasis. ATV was found in biliary calculi in 8 of 11 cases: infrared spectrometry analysis of calculi revealed that ATV made up a median of 89% (range, 10%-100%) of the total calculus composition. Development and management of ATV-associated cholelithiasis are discussed.
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