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Acquisition of GB Virus Type C and Lower Mortality in Patients With Advanced HIV Disease
Author(s) -
Farnaz Vahidnia,
Maya Petersen,
Jack T. Stapleton,
George W. Rutherford,
Michael P. Busch,
Brian Custer
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis589
Subject(s) - medicine , gb virus c , hazard ratio , odds ratio , coinfection , context (archaeology) , immunology , viral load , confidence interval , viral disease , virus , flaviviridae , biology , paleontology
GB virus type C (GBV-C) is transmitted by sexual or parenteral exposure and is prevalent among patients receiving blood products. GBV-C is associated with lower human immunodeficiency virus (HIV) RNA and better survival among HIV-infected patients. Open questions are the presence and the direction of any causal relationship between GBV-C infection and HIV disease markers in the context of highly active antiretroviral therapy (HAART).

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