Interferon Responsiveness Does Not Change in Treatment-Experienced Hepatitis C Subjects: Implications for Drug Development and Clinical Decisions
Author(s) -
Jiang Liu,
J Florian,
Debra Birnkrant,
Jeffrey S. Murray,
Pravin Jadhav
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis510
Subject(s) - medicine , ribavirin , regimen , clinical trial , hepatitis c , interferon , immunology , chronic hepatitis , gastroenterology , virus
The purpose of this research was to compare interferon (IFN) responsiveness in treatment-naive and pegylated interferon α-ribavirin (P/R)-experienced subjects and to understand the implications of comparability in IFN responsiveness across treatment courses on drug development and clinical decision making.
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