Macrolide-Based Regimens and Mortality in Hospitalized Patients With Community-Acquired Pneumonia: A Systematic Review and Meta-analysis
Author(s) -
Leyla Asadi,
Wendy Sligl,
Dean T. Eurich,
Isabelle N Colmers-Gray,
Lisa Tjosvold,
Thomas J. Marrie,
Sumit R. Majumdar
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis414
Subject(s) - medicine , community acquired pneumonia , pneumonia , confidence interval , guideline , relative risk , randomized controlled trial , antibiotics , macrolide antibiotics , intensive care medicine , erythromycin , pathology , microbiology and biotechnology , biology
Macrolides are used to treat pneumonia despite increasing antimicrobial resistance. However, the immunomodulatory properties of macrolides may have a favorable effect on pneumonia outcomes. Therefore, we systematically reviewed all studies of macrolide use and mortality among patients hospitalized with community-acquired pneumonia (CAP).
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