Baseline Platelet Count and Creatinine Clearance Rate Predict the Outcome of Neutropenia-Related Invasive Aspergillosis | Zendy

S. A. Nouer | Zendy; Márcio Nucci | Zendy; Navin Kumar | Zendy; Monica Grazziutti | Zendy; Alejandro Restrepo | Zendy; E. Anaissie | Zendy

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Baseline Platelet Count and Creatinine Clearance Rate Predict the Outcome of Neutropenia-Related Invasive Aspergillosis

Author(s) -

S. A. Nouer,

Márcio Nucci,

Navin Kumar,

Monica Grazziutti,

Alejandro Restrepo,

E. Anaissie

Publication year - 2012

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cis298

Subject(s) - medicine , neutropenia , aspergillosis , creatinine , gastroenterology , absolute neutrophil count , odds ratio , multiple myeloma , renal function , confidence interval , chemotherapy , surgery , immunology

Invasive aspergillosis (IA) is a life-threatening infection for immunocompromised patients. Improvement in IA outcome has been hampered by lack of early prognostic factors, namely, those available before starting chemotherapy (baseline) or early in the course of IA (nonbaseline). We hypothesized that prognostic factors can be identified before chemotherapy, ≤7 days from the first positive serum Aspergillus galactomannan index (s-GMI).

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