Discordance Between CD4+ T-Lymphocyte Counts and Percentages in HIV-Infected Persons With Liver Fibrosis | Zendy

C. Claassen | Zendy; Marie DienerWest | Zendy; Shruti H. Mehta | Zendy; Doneal Thomas | Zendy; Gregory D. Kirk | Zendy

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Discordance Between CD4+ T-Lymphocyte Counts and Percentages in HIV-Infected Persons With Liver Fibrosis

Author(s) -

C. Claassen,

Marie DienerWest,

Shruti H. Mehta,

Doneal Thomas,

Gregory D. Kirk

Publication year - 2012

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cis294

Subject(s) - medicine , cirrhosis , immunology , lymphocyte , human immunodeficiency virus (hiv) , fibrosis , lymphocyte subsets , t lymphocyte , liver fibrosis , viral disease , peripheral blood , t cell , immune system

Cirrhosis of the liver can induce splenic sequestration of peripheral blood cells, recently suggested to reduce the number but not percentage of circulating CD4(+) T cells in persons uninfected with human immunodeficiency virus (HIV). We investigated whether earlier stages of liver fibrosis prior to cirrhosis were associated with discordance between CD4 count (CD4N) and CD4 percentage (CD4%) in HIV-infected patients.

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