How Hidden Can Malaria Be in Pregnant Women? Diagnosis by Microscopy, Placental Histology, Polymerase Chain Reaction and Detection of Histidine-Rich Protein 2 in Plasma
Author(s) -
Alfredo Mayor,
L. Moro,
Ruth Aguilar,
Azucena Bardají,
Pau Cisteró,
Elisa SerraCasas,
Betuel Sigaúque,
Pedro L. Alonso,
Jaume Ordï,
Clara Menéndez
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis236
Subject(s) - medicine , polymerase chain reaction , malaria , histology , pregnancy , histidine , microscopy , obstetrics , virology , pathology , immunology , biochemistry , biology , gene , genetics , amino acid
Accurate diagnosis of malaria infection during pregnancy remains challenging because of low parasite densities and placental sequestration of Plasmodium falciparum. The performance of different methods to detect P. falciparum in pregnancy and the clinical relevance of undetected infections were evaluated.
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