Immune Responses Driven by Protective Human Leukocyte Antigen Alleles From Long-term Nonprogressors Are Associated With Low HIV Reservoir in Central Memory CD4 T Cells
Author(s) -
Benjamin Descours,
Véronique Avettand-Fènoël,
Catherine Blanc,
Assia Samri,
Adeline Mélard,
Virginie Supervie,
Ioannis Theodorou,
Guislaine Carcelain,
Christine Rouzioux,
Brigitte Autran
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cis188
Subject(s) - human leukocyte antigen , immunology , immune system , cd8 , cytotoxic t cell , allele , t cell , antigen , biology , virology , genetics , in vitro , gene
The stable immune control of human immunodeficiency virus (HIV) in long-term nonprogressors (LTNPs) with protective human leukocyte antigen (HLA) alleles raises the question of whether and how these alleles influence the immune distribution of the HIV reservoirs.
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