Impact of Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry on the Clinical Management of Patients With Gram-negative Bacteremia: A Prospective Observational Study | Zendy

Olivier Clerc | Zendy; Guy Prod’hom | Zendy; Christelle Vogne | Zendy; Alain Bizzini | Zendy; Thierry Calandra | Zendy; Gilbert Greub | Zendy

Open Access

Impact of Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry on the Clinical Management of Patients With Gram-negative Bacteremia: A Prospective Observational Study

Author(s) -

Olivier Clerc,

Guy Prod’hom,

Christelle Vogne,

Alain Bizzini,

Thierry Calandra,

Gilbert Greub

Publication year - 2012

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cis1204

Subject(s) - bacteremia , medicine , gram staining , blood culture , prospective cohort study , antibiotics , microbiology and biotechnology , biology

Early identification of pathogens from blood cultures using matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry may optimize the choice of empirical antibiotic therapy in the setting of bloodstream infections. We aimed to assess the impact of this new technology on the use of antibiotic treatment in patients with gram-negative bacteremia.

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