Risk of Progression to Active Tuberculosis Following Reinfection With Mycobacterium tuberculosis
Author(s) -
Jason R. Andrews,
Farzad Noubary,
Rochelle P. Walensky,
Rodrigo Cerda,
Elena Losina,
C. Robert Horsburgh
Publication year - 2012
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cir951
Subject(s) - tuberculosis , medicine , latent tuberculosis , mycobacterium tuberculosis , incidence (geometry) , rate ratio , population , confidence interval , cohort study , cohort , prospective cohort study , immunology , pathology , environmental health , physics , optics
The risk of progression to active tuberculosis is greatest in the several years following initial infection. The extent to which latent tuberculosis infection reduces the risk of progressive disease following reexposure and reinfection is not known. Indirect estimates from population models have been highly variable.
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