-Glucan Antigenemia Assay for the Diagnosis of Invasive Fungal Infections in Patients With Hematological Malignancies: A Systematic Review and Meta-Analysis of Cohort Studies From the Third European Conference on Infections in Leukemia (ECIL-3) | Zendy

Frédéric Lamoth | Zendy; Mario Cruciani | Zendy; Carlo Mengoli | Zendy; Elio Castagnola | Zendy; Olivier Lortholary | Zendy; Malcolm Richardson | Zendy; Oscar Marchetti | Zendy

Open Access

-Glucan Antigenemia Assay for the Diagnosis of Invasive Fungal Infections in Patients With Hematological Malignancies: A Systematic Review and Meta-Analysis of Cohort Studies From the Third European Conference on Infections in Leukemia (ECIL-3)

Author(s) -

Frédéric Lamoth,

Mario Cruciani,

Carlo Mengoli,

Elio Castagnola,

Olivier Lortholary,

Malcolm Richardson,

Oscar Marchetti

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cir897

Subject(s) - medicine , confidence interval , meta analysis , odds ratio , cohort , diagnostic odds ratio , cancer , gastroenterology , immunology

Invasive fungal infections (IFIs) are life-threatening complications in patients with hemato-oncological malignancies, and early diagnosis is crucial for outcome. The compound 1,3-β-D-glucan (BG), a cell wall component of most fungal species, can be detected in blood during IFI. Four commercial BG antigenemia assays are available (Fungitell, Fungitec-G, Wako, and Maruha). This meta-analysis from the Third European Conference on Infections in Leukemia (ECIL-3) assessed the performance of BG assays for the diagnosis of IFI in hemato-oncological patients.

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