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Corticosteroid Therapy for Liver Abscess in Chronic Granulomatous Disease
Author(s) -
Jennifer W. Leiding,
AF Freeman,
B. E. Marciano,
Virgil L. Anderson,
Gülbû Uzel,
Harry L. Malech,
Suk See De Ravin,
David Wilks,
Aradhana M. Venkatesan,
Christa S. Zerbe,
Theo Heller,
Steven M. Holland
Publication year - 2011
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cir896
Subject(s) - medicine , chronic granulomatous disease , refractory (planetary science) , antibiotics , liver abscess , staphylococcus aureus , granulomatous disease , chronic liver disease , abscess , corticosteroid , antibiotic therapy , disease , surgery , immunology , pathology , gastroenterology , bacteria , microbiology and biotechnology , cirrhosis , physics , genetics , astrobiology , biology
Liver abscesses in chronic granulomatous disease (CGD) are typically difficult to treat and often require surgery. We describe 9 X-linked CGD patients with staphylococcal liver abscesses refractory to conventional therapy successfully treated with corticosteroids and antibiotics. Corticosteroids may have a role in treatment of Staphylococcus aureus liver abscesses in CGD.

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