Cytokine Gene Polymorphisms and the Outcome of Invasive Candidiasis: A Prospective Cohort Study | Zendy

Melissa D. Johnson | Zendy; Theo S. Plantinga | Zendy; Esther van de Vosse | Zendy; Digna R. Velez Edwards | Zendy; P. Brian Smith | Zendy; Barbara D. Alexander | Zendy; John C. Yang | Zendy; Dennis Kremer | Zendy; Gregory M. Laird | Zendy; Marije Oosting | Zendy; Leo A. B. Joosten | Zendy; J.W.M. van der Meer | Zendy; Jaap T. van Dissel | Zendy; Thomas J. Walsh | Zendy; John R. Perfect | Zendy; Bart Jan Kullberg | Zendy; William K. Scott | Zendy; Mihai G. Netea | Zendy

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Cytokine Gene Polymorphisms and the Outcome of Invasive Candidiasis: A Prospective Cohort Study

Author(s) -

Melissa D. Johnson,

Theo S. Plantinga,

Esther van de Vosse,

Digna R. Velez Edwards,

P. Brian Smith,

Barbara D. Alexander,

John C. Yang,

Dennis Kremer,

Gregory M. Laird,

Marije Oosting,

Leo A. B. Joosten,

J.W.M. van der Meer,

Jaap T. van Dissel,

Thomas J. Walsh,

John R. Perfect,

Bart Jan Kullberg,

William K. Scott,

Mihai G. Netea

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cir827

Subject(s) - medicine , prospective cohort study , immunology , cytokine , cohort , immune system , cohort study

Candida bloodstream infections cause significant morbidity and mortality among hospitalized patients. Although clinical and microbiological factors affecting prognosis have been identified, the impact of genetic variation in the innate immune responses mediated by cytokines on outcomes of infection remains to be studied.

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