Relationship Between Mycobacterium tuberculosis Phylogenetic Lineage and Clinical Site of Tuberculosis | Zendy

Eleanor S. Click | Zendy; Patrick K. Moonan | Zendy; Carla A. Winston | Zendy; Lauren S. Cowan | Zendy; John E. Oeltmann | Zendy

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Relationship Between Mycobacterium tuberculosis Phylogenetic Lineage and Clinical Site of Tuberculosis

Author(s) -

Eleanor S. Click,

Patrick K. Moonan,

Carla A. Winston,

Lauren S. Cowan,

John E. Oeltmann

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cir788

Subject(s) - tuberculosis , mycobacterium tuberculosis , medicine , odds ratio , lineage (genetic) , genotyping , mycobacterium tuberculosis complex , pathology , biology , genotype , genetics , gene

Genotyping of Mycobacterium tuberculosis has revealed 4 major phylogenetic lineages with differential distribution worldwide. It is not clear whether different lineages are associated with different sites of infection (eg, pulmonary tuberculosis versus extrapulmonary tuberculosis). We sought to determine whether M. tuberculosis lineage is associated with the site of tuberculosis disease.

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