Posaconazole for Chronic Refractory Coccidioidal Meningitis | Zendy

Roland M.H. Schein | Zendy; James Homans | Zendy; Robert A. Larsen | Zendy; Michael Neely | Zendy

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Posaconazole for Chronic Refractory Coccidioidal Meningitis

Author(s) -

Roland M.H. Schein,

James Homans,

Robert A. Larsen,

Michael Neely

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cir734

Subject(s) - medicine , posaconazole , refractory (planetary science) , complication , meningitis , fluconazole , surgery , antifungal , intensive care medicine , dermatology , amphotericin b , physics , astrobiology

Coccidioidal meningitis is a potentially lethal infection. Disease progression while taking fluconazole is a common complication and safe, effective, alternative treatments are limited. Posaconazole therapy resulted in symptomatic and laboratory improvement in 2 patients and clinical improvement in a third patient with chronic, previously unresponsive coccidioidal meningitis.

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