Immunologic Criteria Are Poor Predictors of Virologic Outcome: Implications for HIV Treatment Monitoring in Resource-Limited Settings | Zendy

Holly Rawizza | Zendy; Beth Chaplin | Zendy; Seema Meloni | Zendy; Geoffrey Eisen | Zendy; T.K. Gundu Rao | Zendy; Jean-Louis Sankalé | Zendy; Abdoulaye Dieng-Sarr | Zendy; Oche Agbaji | Zendy; Obinna Onwujekwe | Zendy; Wadzani Gashau | Zendy; Reuben Nkado | Zendy; Ernest Ekong | Zendy; Prosper Okonkwo | Zendy; Robert L. Murphy | Zendy; P. J. Kanki | Zendy

Open Access

Immunologic Criteria Are Poor Predictors of Virologic Outcome: Implications for HIV Treatment Monitoring in Resource-Limited Settings

Author(s) -

Holly Rawizza,

Beth Chaplin,

Seema Meloni,

Geoffrey Eisen,

T.K. Gundu Rao,

Jean-Louis Sankalé,

Abdoulaye Dieng-Sarr,

Oche Agbaji,

Obinna Onwujekwe,

Wadzani Gashau,

Reuben Nkado,

Ernest Ekong,

Prosper Okonkwo,

Robert L. Murphy,

P. J. Kanki

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cir729

Subject(s) - medicine , viral load , immunology , antiretroviral therapy , human immunodeficiency virus (hiv) , intensive care medicine

Viral load (VL) quantification is considered essential for determining antiretroviral treatment (ART) success in resource-rich countries. However, it is not widely available in resource-limited settings where the burden of human immunodeficiency virus infection is greatest. In the absence of VL monitoring, switches to second-line ART are based on World Health Organization (WHO) clinical or immunologic failure criteria.

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