Relapse Versus Reinfection: Surveillance of Clostridium difficile Infection | Zendy

Mini Kamboj | Zendy; Perminder Khosa | Zendy; Anna Kaltsas | Zendy; N. Esther Babady | Zendy; Cheol Son | Zendy; Kent A. Sepkowitz | Zendy

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Relapse Versus Reinfection: Surveillance of Clostridium difficile Infection

Author(s) -

Mini Kamboj,

Perminder Khosa,

Anna Kaltsas,

N. Esther Babady,

Cheol Son,

Kent A. Sepkowitz

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cir643

Subject(s) - medicine , clostridium difficile , diarrhea , typing , clostridiaceae , clostridium , immunology , intensive care medicine , microbiology and biotechnology , antibiotics , bacteria , genetics , toxin , biology

Molecular typing was used to examine surveillance definitions for recurrent Clostridium difficile-associated diarrhea. Among 102 patients, 85 had a second episode within 8 weeks, 88% of which were relapses. Of 49 second episodes occurring after > 8 weeks, 65% were relapses. Categorization of a recurrent episode occurring after >8 weeks as a new infection may misrepresent the majority of episodes for surveillance.

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