Incidence of and Risk Factors for Colistin-Associated Nephrotoxicity in a Large Academic Health System
Author(s) -
Jason M. Pogue,
Jaewon Lee,
Dror Marchaim,
Victoria J. Yee,
Jingjing Zhao,
Teena Chopra,
Paul Lephart,
Keith S. Kaye
Publication year - 2011
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cir611
Subject(s) - nephrotoxicity , colistin , medicine , incidence (geometry) , intensive care medicine , risk factor , environmental health , antibiotics , toxicity , microbiology and biotechnology , biology , physics , optics
Colistin, originally abandoned due to high rates of nephrotoxicity, has been recently reintroduced due to activity against carbapenem-resistant Gram-negative organisms. Recent literature, largely obtained from outside the United States, suggests a lower rate of nephrotoxicity than historically reported.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom