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Incidence of and Risk Factors for Colistin-Associated Nephrotoxicity in a Large Academic Health System
Author(s) -
Jason M. Pogue,
Jaewon Lee,
Dror Marchaim,
Victoria J. Yee,
Jingjing Zhao,
Teena Chopra,
Paul Lephart,
Keith S. Kaye
Publication year - 2011
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cir611
Subject(s) - nephrotoxicity , colistin , medicine , incidence (geometry) , intensive care medicine , risk factor , environmental health , antibiotics , toxicity , microbiology and biotechnology , biology , physics , optics
Colistin, originally abandoned due to high rates of nephrotoxicity, has been recently reintroduced due to activity against carbapenem-resistant Gram-negative organisms. Recent literature, largely obtained from outside the United States, suggests a lower rate of nephrotoxicity than historically reported.

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