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Adherence to Treatment With Artemether-Lumefantrine for Uncomplicated Malaria in Rural Malawi
Author(s) -
Kimberly E. Mace,
Dyson Mwandama,
James Jafali,
M. Luka,
Scott Filler,
J. Sande,
D. Ali,
S. Patrick Kachur,
Don P. Mathanga,
Jacek Skarbinski
Publication year - 2011
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cir498
Subject(s) - medicine , artemether/lumefantrine , lumefantrine , malaria , sulfadoxine/pyrimethamine , regimen , sulfadoxine , odds ratio , logistic regression , pill , artemether , pediatrics , dosing , pyrimethamine , plasmodium falciparum , artemisinin , pharmacology , immunology
In 2007, Malawi replaced the first-line medication for uncomplicated malaria, sulfadoxine-pyrimethamine-a single-dose regimen-with artemether-lumefantrine (AL)-a 6-dose, 3-day regimen. Because of concerns about the complex dosing schedule, we assessed patient adherence to AL 2 years after routine implementation.

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