A Multicenter Evaluation of Tests for Diagnosis of Histoplasmosis | Zendy

Chadi A. Hage | Zendy; Julie A. Ribes | Zendy; Nancy L. Wengenack | Zendy; L. M. Baddour | Zendy; Maha Assi | Zendy; D. S. McKinsey | Zendy; Kassem Hammoud | Zendy; Daisy Alapat | Zendy; N. Esther Babady | Zendy; Monica M. Parker | Zendy; D. Fuller | Zendy; Aliya Noor | Zendy; T. E. Davis | Zendy; Mark Rodgers | Zendy; Patricia Connolly | Zendy; B. Haddad | Zendy; L. J. Wheat | Zendy

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A Multicenter Evaluation of Tests for Diagnosis of Histoplasmosis

Author(s) -

Chadi A. Hage,

Julie A. Ribes,

Nancy L. Wengenack,

L. M. Baddour,

Maha Assi,

D. S. McKinsey,

Kassem Hammoud,

Daisy Alapat,

N. Esther Babady,

Monica M. Parker,

D. Fuller,

Aliya Noor,

T. E. Davis,

Mark Rodgers,

Patricia Connolly,

B. Haddad,

L. J. Wheat

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cir435

Subject(s) - histoplasmosis , medicine , histoplasma , blastomycosis , immunoassay , antigen , immunology , mycosis , urine , antibody , dermatology , histoplasma capsulatum

The sensitivity of the MVista Histoplasma antigen enzyme immunoassay (MiraVista Diagnostics) has been evaluated in disseminated histoplasmosis in patients with AIDS and in the "epidemic" form of acute pneumonia. Moreover, there has been no evaluation of the sensitivity of antigenemia detection in disseminated histoplasmosis after the implementation of methods to dissociate immune complexes and denature released antibodies. The goal of this study was to determine the sensitivity of the current antigen assay in different categories of histoplasmosis.

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