Treatment Outcomes of Isoniazid-Resistant Tuberculosis Patients, Western Cape Province, South Africa | Zendy

Karen R. Jacobson | Zendy; D. Theron | Zendy; T. C. Victor | Zendy; Elizabeth M. Streicher | Zendy; Robin M. Warren | Zendy; Megan Murray | Zendy

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Treatment Outcomes of Isoniazid-Resistant Tuberculosis Patients, Western Cape Province, South Africa

Author(s) -

Karen R. Jacobson,

D. Theron,

T. C. Victor,

Elizabeth M. Streicher,

Robin M. Warren,

Megan Murray

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cir406

Subject(s) - medicine , isoniazid , tuberculosis , cohort , retrospective cohort study , cohort study , pediatrics , pathology

We report treatment outcomes from a retrospective cohort of patients with isoniazid-monoresistant tuberculosis in rural South Africa. Sixteen percent of patients had poor outcomes, 61% of whom progressed to multidrug-resistant tuberculosis. These data reveal the need for early identification and aggressive follow-up of isoniazid monoresistance to increase treatment success.

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