Ocular Manifestations of Candidemia
Author(s) -
Astrid M. L. Oude Lashof,
Aniki Rothová,
Jack D. Sobel,
Markus Ruhnke,
Peter G. Pappas,
Claudio Viscoli,
Haran T. Schlamm,
I. T. Oborska,
John Rex,
Bart Jan Kullberg
Publication year - 2011
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cir355
Subject(s) - medicine , fluconazole , voriconazole , amphotericin b , chorioretinitis , endophthalmitis , mycosis , surgery , incidence (geometry) , randomized controlled trial , ophthalmology , dermatology , antifungal , physics , optics
Ocular candidiasis is a major complication of candidemia. The incidence, risk factors, and outcome of eye involvement during candidemia are largely unknown. We prospectively studied the ocular manifestations of candidemia in a large, worldwide, randomized multicenter trial that compared voriconazole with amphotericin B followed by fluconazole for the treatment of candidemia.
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