Vancomycin Way of Administration: Where is the Evidence?
Author(s) -
Maria Adriana Cataldo,
Evelina Tacconelli,
Federico Pea,
Nicola Petrosillo
Publication year - 2011
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cir343
Subject(s) - medicine , vancomycin , administration (probate law) , intensive care medicine , medline , staphylococcus aureus , bacteria , biology , political science , law , genetics
To the Editor—Vancomycin way of administration in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections is a controversial issue. In daily practice, many clinicians prefer to use continuous infusion (CoI) instead of intermittent infusion (InI), mainly in severe patients admitted in intensive care units (ICUs). Recently published Infectious Diseases Society of America (IDSA) guidelines for the treatment of MRSA infections do not clarify the issue and state that ‘‘because of the lack of a clear benefit over intermittent dosing, and because
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