Ventilator-Associated Tracheitis in Children: Does Antibiotic Duration Matter? | Zendy

Pranita D. Tamma | Zendy; Anne Turnbull | Zendy; Aaron M. Milstone | Zendy; Christoph U. Lehmann | Zendy; Emily Sydnor | Zendy; Sara E. Cosgrove | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Ventilator-Associated Tracheitis in Children: Does Antibiotic Duration Matter?

Author(s) -

Pranita D. Tamma,

Anne Turnbull,

Aaron M. Milstone,

Christoph U. Lehmann,

Emily Sydnor,

Sara E. Cosgrove

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cir203

Subject(s) - medicine , antibiotics , pneumonia , ventilator associated pneumonia , intensive care unit , hazard ratio , retrospective cohort study , confidence interval , microbiology and biotechnology , biology

The optimal duration of antibiotic therapy for ventilator-associated tracheitis (VAT) has not been defined, which may result in unnecessarily prolonged courses of antibiotics. The primary objective of this study was to determine whether prolonged-course (≥7 days in duration) therapy for VAT was more protective against progression to hospital-acquired pneumonia (HAP) or ventilator-associated pneumonia (VAP), compared with short-course antibiotics (<7 days in duration). The secondary objective was to determine whether prolonged-course therapy was more likely to result in the acquisition of multidrug-resistant organisms (MDROs) compared with short-course therapy.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research