Case Report: Treatment of Chronic Osteomyelitis | Zendy

Cameron R. Wolfe | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Case Report: Treatment of Chronic Osteomyelitis

Author(s) -

Cameron R. Wolfe

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cir169

Subject(s) - medicine , osteomyelitis , fusidic acid , amputation , debridement (dental) , surgery , antibiotics , staphylococcus aureus , surgical debridement , osteitis , staphylococcal infections , intravenous antibiotics , microbiology and biotechnology , genetics , biology , bacteria

Presented is a case of chronic methicillin-resistant Staphylococcus aureus osteomyelitis, which was unsuccessfully treated with multiple courses of debridement and potent antibiotic therapies. Amputation of the patient's lower limb was believed to be the only option remaining. A compassionate access program, with approval from the US Food and Drug Administration and the institutional review board, enabled the patient to undergo a course of treatment with oral fusidic acid (CEM-102). The patient tolerated the drug well, with no significant toxicities noted to date. His infection improved rapidly, his flap healed, he has returned to work part-time, and he continues to take daily suppressive doses of oral CEM-102.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research