Decreased Infection-Related Mortality and Improved Survival in Severe Aplastic Anemia in the Past Two Decades | Zendy

Joseph M. Valdez | Zendy; Phillip Scheinberg | Zendy; Óscar Núñez Martínez | Zendy; C. O. Wu | Zendy; NS Young | Zendy; Thomas J. Walsh | Zendy

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Decreased Infection-Related Mortality and Improved Survival in Severe Aplastic Anemia in the Past Two Decades

Author(s) -

Joseph M. Valdez,

Phillip Scheinberg,

Óscar Núñez Martínez,

C. O. Wu,

NS Young,

Thomas J. Walsh

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciq245

Subject(s) - medicine , neutropenia , aplastic anemia , multivariate analysis , hematology , absolute neutrophil count , anemia , mortality rate , gastroenterology , immunology , chemotherapy , bone marrow

Persistent neutropenia associated with severe aplastic anemia (SAA) is an important risk factor for development of life-threatening infections. Earlier studies underscored the high mortality associated with invasive fungal infections (IFIs) in SAA. However, little is known about the current patterns of infections and the impact of advances in anti-infective therapy on survival in SAA.

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