No Risk of Myocardial Infarction Associated With Initial Antiretroviral Treatment Containing Abacavir: Short and Long-Term Results from ACTG A5001/ALLRT
Author(s) -
Heather J. Ribaudo,
Constance A. Benson,
Yu Zheng,
Susan L. Koletar,
Ann C. Collier,
Judith J. Lok,
Marlene Smurzynski,
Ronald J. Bosch,
B. Bastow,
Jeff Schouten
Publication year - 2011
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciq244
Subject(s) - abacavir , medicine , hazard ratio , confounding , myocardial infarction , proportional hazards model , population , confidence interval , regimen , human immunodeficiency virus (hiv) , viral load , immunology , antiretroviral therapy , environmental health
Observational and retrospective clinical trial cohorts have reported conflicting results for the association of abacavir use with risk of myocardial infarction (MI), possibly related to issues that may bias estimation of treatment effects, such as time-varying confounders, informative dropout, and cohort loss due to competing events.
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