Frequency of Drug-resistant Viruses and Virus Shedding in Pediatric Influenza Patients Treated With Neuraminidase Inhibitors | Zendy

Daisuke Tamura | Zendy; Norio Sugaya | Zendy; Makoto Ozawa | Zendy; Ryo Takano | Zendy; Masataka Ichikawa | Zendy; Masahiko Yamazaki | Zendy; Chiharu Kawakami | Zendy; Hideaki Shimizu | Zendy; Ritei Uehara | Zendy; Maki Kiso | Zendy; Eiryo Kawakami | Zendy; Keiko Mitamura | Zendy; Yoshihiro Kawaoka | Zendy

Open Access

Frequency of Drug-resistant Viruses and Virus Shedding in Pediatric Influenza Patients Treated With Neuraminidase Inhibitors

Author(s) -

Daisuke Tamura,

Norio Sugaya,

Makoto Ozawa,

Ryo Takano,

Masataka Ichikawa,

Masahiko Yamazaki,

Chiharu Kawakami,

Hideaki Shimizu,

Ritei Uehara,

Maki Kiso,

Eiryo Kawakami,

Keiko Mitamura,

Yoshihiro Kawaoka

Publication year - 2011

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciq183

Subject(s) - zanamivir , oseltamivir , neuraminidase , neuraminidase inhibitor , virology , virus , medicine , influenza a virus , orthomyxoviridae , influenza a virus subtype h5n1 , drug resistance , viral shedding , microbiology and biotechnology , biology , infectious disease (medical specialty) , covid-19 , disease

Although influenza virus resistance to the neuraminidase inhibitor zanamivir is reported less frequently than is resistance to the neuraminidase inhibitor oseltamivir in clinical settings, it is unknown whether this difference is due to the limited use of zanamivir or to an inherent property of the drug. We therefore compared the prevalence of drug-resistant viruses and virus shedding in seasonal influenza virus-infected children treated with either oseltamivir or zanamivir.

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