Comparison of Oral Amoxicillin with Placebo for the Treatment of World Health Organization-Defined Nonsevere Pneumonia in Children Aged 2-59 Months: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial in Pakistan | Zendy

Tabish Hazir | Zendy; Yasir Bin Nisar | Zendy; Saleem Abbasi | Zendy; Yusra Pervaiz Ashraf | Zendy; Javaid Khurshid | Zendy; Perween Tariq | Zendy; Rai Muhammad Asghar | Zendy; A. Murtaza | Zendy; Tahir Masood | Zendy; S Maqbool | Zendy

Open Access

Comparison of Oral Amoxicillin with Placebo for the Treatment of World Health Organization-Defined Nonsevere Pneumonia in Children Aged 2-59 Months: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial in Pakistan

Author(s) -

Tabish Hazir,

Yasir Bin Nisar,

Saleem Abbasi,

Yusra Pervaiz Ashraf,

Javaid Khurshid,

Perween Tariq,

Rai Muhammad Asghar,

A. Murtaza,

Tahir Masood,

S Maqbool

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciq142

Subject(s) - medicine , amoxicillin , pneumonia , placebo , randomized controlled trial , odds ratio , pediatrics , antibiotics , alternative medicine , pathology , microbiology and biotechnology , biology

world Health Organization (WHO) acute respiratory illness case management guidelines classify children with fast breathing as having pneumonia and recommend treatment with an antibiotic. There is concern that many of these children may not have pneumonia and are receiving antibiotics unnecessarily. This could increase antibiotic resistance in the community. The aim was to compare the clinical outcome at 72 h in children with WHO-defined nonsevere pneumonia when treated with amoxicillin, compared with placebo.

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