Directly Selected Cytomegalovirus-Reactive Donor T Cells Confer Rapid and Safe Systemic Reconstitution of Virus-Specific Immunity Following Stem Cell Transplantation | Zendy

Karl S. Peggs | Zendy; Kirsty Thomson | Zendy; Edward Samuel | Zendy; Gemma Dyer | Zendy; Julie Armoogum | Zendy; Ronjon Chakraverty | Zendy; K. H. Pang | Zendy; Stephen Mackin | Zendy; Mark W. Lowdell | Zendy

Open Access

Directly Selected Cytomegalovirus-Reactive Donor T Cells Confer Rapid and Safe Systemic Reconstitution of Virus-Specific Immunity Following Stem Cell Transplantation

Author(s) -

Karl S. Peggs,

Kirsty Thomson,

Edward Samuel,

Gemma Dyer,

Julie Armoogum,

Ronjon Chakraverty,

K. H. Pang,

Stephen Mackin,

Mark W. Lowdell

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciq042

Subject(s) - adoptive cell transfer , cd8 , transplantation , immunology , cytotoxic t cell , medicine , stem cell , t cell , immunity , immune system , virology , biology , in vitro , microbiology and biotechnology , biochemistry

Adoptive transfer of virus-specific T cells may accelerate reconstitution of antigen-specific immunity and limit the morbidity and mortality of viral infections following allogeneic hematopoietic stem cell transplantation. The logistics of producing virus-specific T cells has, however, limited the application of cellular therapies, particularly following the introduction of more-recent regulatory stipulations.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research