Virus Detection and Duration of Illness Among Patients With 2009 Pandemic Influenza A (H1N1) Virus Infection in Texas | Zendy

Anil Suryaprasad | Zendy; Oliver Morgan | Zendy; Patrick Peebles | Zendy; Agnes K. Warner | Zendy; Tara Kerin | Zendy; Mathew D. Esona | Zendy; Michael D. Bowen | Zendy; Wendy Sessions | Zendy; Xiyan Xu | Zendy; Theresa L. Cromeans | Zendy; Fatimah S. Dawood | Zendy; Trudi Shim | Zendy; Manoj Me | Zendy; Jennifer R. Verani | Zendy; Dean D. Erdman | Zendy; Stephen Lindstrom | Zendy; Vincent P. Fonseca | Zendy; Alicia M. Fry | Zendy; Sonja J. Olsen | Zendy

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Virus Detection and Duration of Illness Among Patients With 2009 Pandemic Influenza A (H1N1) Virus Infection in Texas

Author(s) -

Anil Suryaprasad,

Oliver Morgan,

Patrick Peebles,

Agnes K. Warner,

Tara Kerin,

Mathew D. Esona,

Michael D. Bowen,

Wendy Sessions,

Xiyan Xu,

Theresa L. Cromeans,

Fatimah S. Dawood,

Trudi Shim,

Manoj Me,

Jennifer R. Verani,

Dean D. Erdman,

Stephen Lindstrom,

Vincent P. Fonseca,

Alicia M. Fry,

Sonja J. Olsen

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciq014

Subject(s) - medicine , pandemic , virus , virology , influenza a virus , covid-19 , human mortality from h5n1 , influenza like illness , h1n1 influenza , pandemic influenza , infectious disease (medical specialty) , outbreak , disease

Knowledge from early outbreaks is limited regarding the virus detection and illness duration of the 2009 pandemic influenza A (H1N1) infections. During the period from April to May 2009 in Texas, we collected serial nasopharyngeal (NP) and stool specimens from 35 participants, testing by real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) and culture. The participants were aged 2 months to 71 years; 25 (71%) were under 18. The median duration of measured fever was 3.0 days and of virus detection in NP specimens was 4.2 days; however, few specimens were collected between days 5-9. The duration of virus detection (4.2 days) was similar to the duration of fever (3.5 days) (RR, 1.14; 95% CI, .66-1.95; P = .8), but was shorter than the duration of cough (11.0 days) (RR, .41; 95% CI, .24-.68; P < .001). We detected viral RNA in two participants' stools. All cultures were negative. This investigation suggests that the duration of virus detection was likely similar to the seasonal influenza virus.

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