Estimating the Burden of 2009 Pandemic Influenza A (H1N1) in the United States (April 2009-April 2010) | Zendy

Sundar S. Shrestha | Zendy; David L. Swerdlow | Zendy; Rebekah H. Borse | Zendy; Vimalanand S. Prabhu | Zendy; L. Finelli | Zendy; Charisma Y. Atkins | Zendy; Kwame OwusuEdusei | Zendy; Beth P. Bell | Zendy; Paul S. Mead | Zendy; Matthew Biggerstaff | Zendy; Lynnette Brammer | Zendy; Harriet Davidson | Zendy; Daniel B. Jernigan | Zendy; Michael A. Jhung | Zendy; Laurie Kamimoto | Zendy; Toby L. Merlin | Zendy; Mackenzie Nowell | Zendy; Stephen C. Redd | Zendy; Carrie Reed | Zendy; Anne Schuchat | Zendy; Martin I. Meltzer | Zendy

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Estimating the Burden of 2009 Pandemic Influenza A (H1N1) in the United States (April 2009-April 2010)

Author(s) -

Sundar S. Shrestha,

David L. Swerdlow,

Rebekah H. Borse,

Vimalanand S. Prabhu,

L. Finelli,

Charisma Y. Atkins,

Kwame OwusuEdusei,

Beth P. Bell,

Paul S. Mead,

Matthew Biggerstaff,

Lynnette Brammer,

Harriet Davidson,

Daniel B. Jernigan,

Michael A. Jhung,

Laurie Kamimoto,

Toby L. Merlin,

Mackenzie Nowell,

Stephen C. Redd,

Carrie Reed,

Anne Schuchat,

Martin I. Meltzer

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciq012

Subject(s) - medicine , pandemic , disease control , public health , demography , covid-19 , influenza pandemic , influenza a virus , environmental health , disease , infectious disease (medical specialty) , virology , virus , nursing , sociology

To calculate the burden of 2009 pandemic influenza A (pH1N1) in the United States, we extrapolated from the Centers for Disease Control and Prevention's Emerging Infections Program laboratory-confirmed hospitalizations across the entire United States, and then corrected for underreporting. From 12 April 2009 to 10 April 2010, we estimate that approximately 60.8 million cases (range: 43.3-89.3 million), 274,304 hospitalizations (195,086-402,719), and 12,469 deaths (8868-18,306) occurred in the United States due to pH1N1. Eighty-seven percent of deaths occurred in those under 65 years of age with children and working adults having risks of hospitalization and death 4 to 7 times and 8 to 12 times greater, respectively, than estimates of impact due to seasonal influenza covering the years 1976-2001. In our study, adults 65 years of age or older were found to have rates of hospitalization and death that were up to 75% and 81%, respectively, lower than seasonal influenza. These results confirm the necessity of a concerted public health response to pH1N1.

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